Mirailab Bioscience’s NMN
About the manufacturing method of complete β-type NMN
International patent pending
Mirailab Bioscience is a pioneering biotechnology venture that has been at the forefront of NMN research in Japan since early on, offering NMN that is not only safer but also of the highest quality compared to anywhere else.
1. The only NMN products recognized by the world-leading authority on NMN research, Professor Shin-ichiro Imai.
Professor Shin-ichiro Imai, who broke new ground with his research on NMN, blows the whistle on the pandemonium of NMN capsules available on the market at present, and Mirai Lab’s Pure Series are the very products he can rely on. Mirai Lab’s NMN Pure series boasts absolute purity with the approval of a leading expert. This NMN does not contain impurities or forms of NMN not produced naturally in our bodies.
2. We were the first in commercializing NMN
and we are the only company in Japan
having a research facility dedicated to NMN.
Commercialization focused on research on NMN, which is rapidly making the medical industry progress. We established our original supplement brand Mirai Lab and started making sales. Many NMN companies cite scientific papers published by anti-aging researchers or request external inspections from food analysis centers, but do not perform analysis using their own laboratories. Mirailab Bioscience is the only company in Japan that owns an in-house NMN research laboratory.
3. We conducted the world’s first safety test on humans Academia-quality NMN used in cutting-edge clinical research
Mirai Lab’s NMN was the first in the world to be used in a safety test on humans (*). In addition to demonstrating its safety, we confirmed the expression of the sirtuin genes, an increase in melatonin and other growth hormones in a long-term (24-week) administration clinical study at Hiroshima University School of Medicine. These achievements and its purity are highly considered, and our NMN products were selected as a test food to be used in a new clinical research at the Washington University in St. Louis, School of Medicine, led by Professor Shin-ichiro Imai, an authority on NMN.
※UMIN-ICDR For details, click here
4. Our NMN has an absolute purity of 99.7% (1), according to a fair and transparent “absolute measurement method.” By “impurity” we mean a substance that’s harmless to humans
The absolute measurement method quantifies what percentage of all substances detected in the sample is NMN, and indicates the purity with reference to NMN. On the other hand, the relative measurement method shows the relative value with reference to a “standard NMN” which is considered 100% pure. Surprisingly, the “standard NMN” in this second method can be supplied by the manufacturer itself, and its purity is not disclosed. Mirai Lab’s NMN achieves an absolute purity of 99.7% (1), and when compared with other companies’ products as shown below, the purity of Mirai Lab’s NMN exceeds 100% in relative purity. This explains well by itself the overwhelming purity of Mirai Lab’s products.
(1) Purity analysis by the Institute for Research on Productive Aging (IRPA)
(2) Analysis by high performance liquid chromatography and ultraviolet absorption spectroscopy
(3) Analysis by nuclear magnetic resonance spectroscopy
Differences in methods for measuring NMN purity
There are two different measuring methods: the absolute method and the relative method.
We employ the absolute method, which shows objectively how much is NMN, from all the substances found in a sample.
Absolute purity determined
by a precise method
Purity determined by a relative measurement method
Also, according to another analysis that determines the identity of the impurities found in the first test, the only impurity detected in our NMN is nicotinamide, a substance humans can ingest with total safety.
Impurities in NMN samples
Please note that there are products from other brands available on the market that claim to contain high-purity NMN, while they may actually contain low-quality NMN whose safety has not been confirmed.
Tests carried out by the Institute for Research on Productive Aging (IRPA.)
5. The effects of α-NMN in our bodies is unknown.
We only give you full β-NMN, the NMN your body needs.
NMN exists with two different molecular structures: α-NMN and β-NMN. The NMN that we need is β-NMN, which is naturally generated in our bodies. The other NMN, α-NMN, is something we don’t need and something not produced in us. Mirai Lab is offers you NMN supplements with the only NMN you should care about: β-NMN.
About optical isomerism
α-NMN and β-NMN have the same types and numbers of components (atoms) that make up the molecule, but the orientation of the connections between these components (atoms) is different, and they are referred to as optical isomers.
The schematic representation of the molecular structures of α-NMN and β-NMN is shown in the figure to illustrate their differences.
About the manufacturing method of complete β-type NMN
International Patent Pending