Mirailab Bioscience Inc. (Headquarters: Chuo-ku, Tokyo; CEO: Nobuaki Shimizu) will launch its new oral supplement, “NMNH LX,” on Friday, June 12, 2026. This next-generation supplement is formulated with beta-nicotinamide mononucleotide reduced (β-NMNH), the reduced form of β-NMN. Retail price: 540,000 yen (tax included)(For details on the launch date, please check “About Our Online Shop” below.)
This product goes beyond the traditional concept of merely “replenishing what is lost.” It was developed with a completely new perspective: “optimizing the balance of the body’s entire internal environment.”
NMN represents a rational solution for addressing the decline of intracellular NAD⁺ that occurs with aging (Reference 1). NMNH is our alternative breakthrough—an entirely new answer born from the quest to sustain inner cellular balance.
■A Novel Approach: Focusing Not Just on “Deficiencies,” But on “Imbalances”
Until today, oral anti-aging supplements have primarily revolved around the methodology of “supplementing”—literally replenishing the components that decline with age.
Yet, the human body is far more than a simple equation. It is not just about the quantity of a nutrient, but its quality—not just “how much is there,” but “how is it behaving?”
Mirailab has reframed from the changes associated with aging. Rather than viewing them as a mere “deficiency,” we see them as an “imbalance” accumulated as biological systems adapt to their environment.
■What is NMNH?
NMNH is the reduced form of the NMN molecule. Cellular energy metabolism fundamentally relies on a dynamic process in which the oxidized form (NAD⁺) and the reduced form (NADH) continuously interconvert.
Think of NAD⁺ as an empty cup, and NADH as the cup filled with energy. To put it another way, NADH is a “charged battery,” while NAD⁺ is a “drained, empty battery.”
The crucial point here is to look beyond just how many of these energy carriers (NAD⁺ and NADH) are present, and to also consider which state they are in.
Just as NMN is converted into NAD⁺ (the discharged battery) within the cells, NMNH is converted into NADH (the charged battery).
＜Reference＞
Molecular Structure: NMN vs. NMNH
Image attached below
■Research and Development Initiated in 2021
In 2021, a research group from the University of Amsterdam (Netherlands) published a study demonstrating that NMNH has the potential to increase intracellular NAD⁺ levels more efficiently than NMN (Reference 2).
The researchers at Mirailab’s laboratory in Nihonbashi, Tokyo at that time were captivated not only by the compound’s ability to boost NAD⁺ levels, but also by the unique structural features of the NMNH molecule. They recognized a clear structural analogy: the relationship between NMN and NMNH beautifully mirrored the connection between NAD⁺ and NADH, which forms the very foundation of cellular energy metabolism.
■Our Commitment to Quality Assurance and Safety
In preparation for the commercialization of our NMNH-infused supplements, Mirailab collaborated with external institutions to conduct comprehensive quality verifications. Multifaceted evaluations—including body composition, physique indices, vital signs, urinalysis, and blood tests—were performed and are maintained as part of our rigorous quality control documentation.
Furthermore, production is carried out under strict quality assurance frameworks at Japan-based, GMP-compliant manufacturing plants.
■Recommended For
・Have been consistently taking NMN and are ready for the next step.
・Are interested in a novel wellness approach that goes beyond simply “replenishing quantity.”
・Want to support their daily life rhythms and optimize the balance of their internal environment.
・Are mindful of changes in their physical condition as they age.
・Wish to elevate or rethink their daily health and wellness routines.
■References
1. https://pubmed.ncbi.nlm.nih.gov/29514064/
2. https://pubmed.ncbi.nlm.nih.gov/33724555/
■商品概要
| Product Name | NMNH LX |
| Retail Price | 540,000Yen (tax included) |
| Release Date | Friday, June 12, 2026 Nihombashi Mitsukoshi Main StoreWednesday, July 1, 2026, at 12:00 AM (Midnight) Official Online ShopWednesday, July 1, 2026, at 11:00 AM Flagship Store: MIRAILAB Wellness Branch |
| Content | 9.27 g（309 mg×30capsules） |
| Country of Origin | JAPAN |
| Nutrition | Per serving: 1 capsule (309 mg) Calories: 0.75 kcal / Protein: 0.07 g / Total Fat: 0.01 g /Total Carbohydrate: 0.10 g / Salt: 0.05 g |
| Ingredients | Reduced β-nicotinamide mononucleotide (NMNH) (domestic manufacture), starch, starch hydrolysate / HPMC, sucrose fatty acid ester, fine silicon dioxide |
| Directions | As a dietary supplement, take 1 capsule daily with water or warm water. |
| Storage | Store in a cool, dry place away from direct sunlight. |
| Precautions | ・Do not consume if you have food allergies. Discontinue use immediately if you experience any adverse reactions or feel that it does not suit your body. ・ If you are taking medication or under medical supervision, consult your doctor before use. ・This product is not intended to cure diseases or improve health through excessive intake. Please adhere to the recommended daily intake. ・Keep out of reach of children. ・Consume as soon as possible after opening the individual package. |
■About Our Shop
You can purchase our products at the following shops.
1）Friday, June 12, 2026
Relaxing Laboratory/Promotion (Mirailab)
5th Floor, Main Building, Nihombashi Mitsukoshi Main Store
Address: 1-4-1 Nihombashi Muromachi, Chuo-ku, Tokyo 103-8001
Tel: +81-3-3241-3311 (Main)
https://www.mistore.jp/store/nihombashi/access.html
*End date: To be determined (TBD)
*Please visit the official Nihombashi Mitsukoshi Main Store website prior to your visit to confirm the latest business hours, operating days, and event updates.
2）Wednesday, July 1, 2026, from 11:00 AM (Scheduled)
Mirailab Official Online Shop
https://mirai-lab.jpn.com/
3）Wednesday, July 1, 2026, from 11:00 AM (Scheduled)
MIRAILAB Wellness Branch (Flagship Store)
Address: 1F Dai-3 Ginza Yamato Bldg., 2-11-10 Ginza, Chuo-ku, Tokyo 104-0061, Japan
Tel: +81-3-6243-3082
https://www.mirailab-bio.com/mirailabwellnessbranch/
■About Mirailab Bioscience
Embodying our brand philosophy, “The Luxury of Science,” Mirailab Bioscience operates a life science business dedicated to exploring the future of beauty and health through the lens of advanced life sciences.
■Contact Information
Please direct all inquiries to the following:
Mirailab Bioscience Inc.
https://www.mirailab-bio.com/contact